August 17, 2016 / como / 0 Comments
1. Matrixyl
The most popular signal peptide for cosmetic use is palmitoyl pentapeptide (Matrixyl). Palmitoyl pentapeptide-4 (Matrixyl) is a skin rejuvenation compound. The palmitoyl pentapeptide consists of five amino acids linked together and attached to a fatty acid to enhance oil solubility for the sake of better skin penetration. It stimulates the synthesis of the key constituents of the skin matrix: collagen, elastin and glucosamnoglycans because it is structurally related to the precursor of collagen type I.
2. Copper peptides: Argireline
Because peptides are small, they can penetrate the skins protective barriers to get to the deeper layers. When copper is attached to a peptide, the peptide can deliver copper to the living layers of the skin. Copper is essential for enzymes including lysyl oxidase (crosslinking of elastin and collagen) and dopamine beta hydroxylase (catecholamine formation). Copper Peptide products show positive effects on collagen deposition, tensile strength, angiogenesis, hair follicle cycle regulation, and SOD activity so that to diminish the appearance of fine lines and wrinkles. Copper peptides can be found in Neova, Osmotics as well as products like Neutrogenas Visibly Firm Night Cream.
Some Neuropeptides might block transmission of signals from nerves to your facial muscles. Argireline is the trade name for Acetyl Hexapeptide-3, a synthetic anti-aging cosmetic ingredient derived from natural proteins. Argirelines purpose is to decrease the visible effects of aging by reducing the deep wrinkles and lines that occur around the forehead and eyes. Cosmetics companies have marketed Argireline as a cheaper alternative treatment to Botulinum Toxin A (Botox), because the principles behind their chemical actions are similar.
3. Other cosmetic peptides: Matrikine
Other peptides like matrikine peptide (glycyl-histidyl-lysine) are small peptide fragments of extracellular matrix proteins that display potent tissue repair activities. It is possible to use matrikine peptide incorporated collagen film as a therapeutic agent in the wound healing process. Some cosmetic preparation contains peptide derivatives from -MSH. These cosmetic products have the property of activating the melanogenesis and being an anti-inflammatory and acting more efficiently.
4. Peptide might not do anything
Unfortunately, the clinical data is still too skimpy to view many peptides such as palmitoyl pentapeptide-4 as a proven anti-wrinkle treatment at this time. Peptides are break-down products of proteins. They might continue to break down further in a topical cream, becoming useless. A difficulty in achieving sustained delivery of bioactive concentration of some cosmetic peptides in the affected area limits their therapeutic use.
February 17, 2016 / como / 0 Comments
With the age increasing, the body protection is decreased. Physiological damage caused by lipid peroxidation, especially reactions that endogenous superoxide free radicals in the body in the unsaturated fatty acids, resulting in unstable lipid peroxidation, and thus the decomposition of aldehydes, especially malondialdehyde aldehyde, which attacks phospholipids and proteins by the reaction to form lipid-protein complex, lipofuscin deposition in the cell, as a sign of cellular aging. Therefore, prevention and anti-oxidant has been a powerful tool for the treatment of skin aging, but also an important way for many other compounds to achieve anti-aging skin effect.
Are commonly used antioxidants include substances such as enzymes or enzymes of vitamin A, vitamin E, cysteine, ascorbic acid, superoxide dismutase, glutathione peroxidase, metallothionein, sulfhydryl papaya enzyme, coenzyme Q10 and so on. And some amino acids such as glycine, serine and salicylaldehyde with iron to form the condensation product 2: l complexes, inhibited by the reaction with hydroxyl radicals of iron-related, and can inhibit lipid peroxidation, also has anti- oxidation. Melatonin, estrogen and other hormones and is also related to reports.
Superoxide dismutase (SOD) is the most in-depth study of cosmetics, the most widely used anti-oxidants, contain copper, zinc, manganese and iron metalloenzyme, widely present in various tissues of organisms, is the only to specific antioxidant enzyme superoxide anion. SOD from cattle, pigs and other extracts of red blood cells, also from spinach, cabbage, prickly pear, yeast and bacterial extracts. Now know that at least Cu. SOD, Mn. SOD, Fe-SOD, Zn-SOD and EC-SOD in five different SOD. SOD activity of the enzyme used as a cosmetic ingredient as affected by many factors, such as short half-life in vivo residence time is short, usually only 6-20min: 32 000 molecular weight around easily through the stratum corneum and the cell membrane and has antigenic and so on. To address these negative factors, the major domestic use molecular engineering approach to heparin, polyethylene glycol, dextran, biotin and other water-soluble macromolecules to their non-active groups or the use of molecular modifications to increase its transdermal absorption of liposomes, etc. embedding the new carrier.
Vitamin E, C is the first cosmetic application of anti-oxidants, a natural antioxidant, and their main function is to reduce the damage of living cells with hydrogen peroxide, superoxide anion and hydroxyl generation. Main role: vitamin E can reduce eye burn of erythema, which may be due to removal of oxygen free radicals induced by UV radiation, the reason: vitamin C is unstable in aqueous solution, it is difficult to be absorbed through the skin. In a proprietary formula, vitamin C preparations added zinc and tyrosine (Cellex-C), topical, the vitamin C levels in the skin 20 times higher than normal, the depth of penetration into the dermis 500 U m, tretinoin from the anti- oxidation, can block ultraviolet UVA and UVB damage to the organization.
In addition, vitamin C is considered a cellular factor that can directly stimulate fibroblasts to produce collagen. Vitamin C is a necessary component of collagen metabolism. L-ascorbic acid-2-phosphate magnesium (VC-PMG) is another vitamin C preparations patented formula, which is more stable compounds have been used in Japan to pigmentation agent. In addition, the element germanium (Ge32) and certain herbal and marine extracts also has antioxidant effects reported.
August 11, 2015 / como / 0 Comments
Dabao
“Great Treasure” series Cosmetics was born in 1985;
During the period 1985 to 1990 consumer launch of the speed honey eyes wrinkles, age spots cream, bags under the eyes cream and other products sold at home and abroad is not a long decline, is known so far;
So far in 1993, best-selling beauty day cream, night cream, and honey, like SOD household, with an annual sales volume of about 14 million bottles;
In 1994 to market the MT series of cosmetics in the country opened up to metallothionein (English short MT) such substances used for cosmetics set a precedent for accelerated penetration of nutrients into the skin and the internal rate to prevent skin aging effect is more obvious, has opened up new areas of application of cosmetic raw materials.
Consumer Hot Zan products: canthus wrinkle honey (main ingredient of pollen), bags under the eyes cream, eye cream (nourishment, but can not afford to Zhifang Li), hand, foot care cream, SOD honey, beauty night cream, beauty facial cleanser (North Shadow girls favorite)
Note: The Great Treasure of products basically contain ginseng and astragalus.
In Japan, many products have a Made in China logo. Previously, such a sign of just being seen as a bargain or a symbol of inferior goods, but now, many international top brands which also appeared more and more Made in China. Many Japanese from China back to Japan that it will take a lot of “great treasure.” Cosmetics shop in Japan, “Da Bao” in China, but worth the price of more than 10 times oh.
2, Pulanna (Miss World Finals is the only designated skin care)
Brand Description: Pulanna, from French, “les plantesnaturelles (natural plant)” in Chinese transliteration, she uphold the essence of Chinese classical Yang Fu school, integration herbal essence and the latest achievements of modern biotechnology, through 20 years of carefully orchestrated , so that the ancient beauty Kampo shine, the creation of Pulanna Oriental beauty of the Kingdom. Is China’s first high-tech exports of cosmetics. Over the years, Pulanna in the international community has won the French “Beyond Beautiful” International Beauty Show gold medal awards at home and abroad, etc. 85. In 2005, Pulanna skin care brands to rewrite the Western monopoly of the history of the Miss World event, becoming the 55th Miss World Final is the only designated skin care products, and was awarded the Special Contribution Award. At present, cosmetics, natural vegetation has been marketing Pulanna 98 countries and regions in the world as the world’s hundreds of millions of the public, “skin care experts.”
3, Nanjing Golden Ballet (the first veteran to enter Europe and the United States)
Brand Description: ballet, was born in 1933, with the experience of centuries of Perfumery, as early as 70 years entered the Europe and America, Southeast Asian market, many in the international counterparts to get the praise, is China’s Hong vice president of the Association of the governing unit.
The seventies, China’s first natural-based cosmetics, nutritional “pearl cream” In the hands of people from the ballet, and “a hero to enter the Hong Kong market” has become China’s first cosmetics export enterprises inside and outside a sensation in one fell swoop. Eighties, the first natural mink oil and silk protein as the main raw material a series of cosmetics, in order to crack cold rule, a unique skin nourishing moisturizing effect, well received by the consumer’s love and salable.
Even today, “ballet mink ointment” still dominate the cosmetics market dominance.
Consumer Hot Zan Products: Ballet Pearl Cream (still popular favorite), ballet mink ointment
Mink oil and human skin has excellent permeability and compatibility. Nutrition, moisturizing, easily absorbed. Frequent use, nutrition, skin moisture, so resilient and has good cold crack effect.
4, deeply love Royal Empress mud Square
Brand Description: In the Qing dynasty Qianlong “beachhead powder paper” has come out. Locally they are called “Pak Nai.” This “Nai,” dozens of kinds of rich minerals, in the human skin has a physiotherapy role in Beauty and skin care and has a magical effect. Historical records from the current world has not yet been found to have a second place of origin, can be described as unique in the world of rare and unique mineral mud.
The Qing dynasty period (1875-1909) to the unique Nai powder as raw materials of paper popular among women. Tribute tribute to the imperial court had won the popular Empress Dowager Cixi, so mud is called “Royal mud”! In the initial stage, are exported to Europe and the United States and Japan; have skin is still semi-finished products exported to Japan and other countries. CCTV and Hunan Satellite TV have reported to the company.
Consumer Hot Zambia Products: Imperial Square Revitalizing Mineral Mud Mask Mud (used people say that the green clay than Begas easy to use, effective cleaning without stimulation)
5, Herborist
Herborist Han Fang beauty concepts are gradually enjoys popular support, in particular about the national character of modern times, Chinese people need not to over-dependence on foreign cosmetics. Our skin care brand purchased from foreign countries when in fact a lot of foreigners are to Kampo beauty for foreign use. Japan is now the best-selling beauty book is neither a “cosmetic king” is not “beautiful people up,” but rather by the Japanese Yuko Takagi, senior beauty experts to write “Chinese cosmetic adventure.” Ginseng, astragalus, Chinese angelica, pearl, aloe, pollen, sandalwood, Poria, beauty beauty UFA Toothpaste. Do not forget, they are precious to our ancestors.
Consumer Hot Zan products: Herborist tender skin whitening mask 500g, Herborist Balance Lotion 50ML